The Astros haven't enjoyed much success since they last faced the Angels.
Houston has lost 18 of its last 22 games since it had a three-game winning streak snapped on April 13 in Anaheim. The Astros have dropped six games in a row and are coming off a sweep at home against the Tigers, allowing 37 runs in four games.
But the Angels have been through their share of struggles as well, losing nine of their last 11.
The clubs will have a chance to regroup Monday before beginning a three-game series Tuesday at Minute Maid Park.
The Angels have lost 11 of their last 14 road games, but Astros manager Bo Porter knows they are still a dangerous team.
"I don't look at the fact they're not playing their best ball," Porter said. "I said this when we were in Anaheim, when you have the type of roster they have and players capable of playing to the level they can play, you would almost prefer them to be hot and stay hot and say to yourself, 'Maybe they'll cool off when they come in here.' I don't look at anything that anybody else says about how they're playing. We're going to have to play our best baseball to play well against them."
Angels outfielder Mark Trumbo has done all he can to keep the club afloat with five homers in his last six games. He's one of a handful of Major Leaguers to reach base in 30 games.
"He's been everything we were looking for, and it's obvious with him being bumped in the middle of our lineup the confidence we have that he can continue," said Angels manager Mike Scioscia.
C.J. Wilson will start for the Angels in the series opener. The left-hander leads the team with three wins and 32 strikeouts. He earned his first win of the season on April 14 against Houston, allowing one run in six innings.
Jordan Lyles will make his second start this year for the Astros. He pitched well on Thursday against Detroit, allowing two runs and six hits in five innings. He left the game with a 3-2 lead, but the Astros lost, 7-3, in 14 innings.
Angels: Pujols looks to continue Houston success
Albert Pujols is very familiar with Minute Maid Park, and he put up strong numbers there during his 11 seasons with the Cardinals, the Astros' former division rival. The first baseman has a career .311 average in 92 games at the ballpark with 24 homers, 16 doubles and 50 RBIs.
Pujols was not in the lineup Sunday, but is likely to return Tuesday. He's been playing despite plantar fasciitis in his foot. Pujols has been getting treatment daily on his foot, but the club "stepped it up" Saturday in hopes of improving his health for Tuesday.
"I think it's good for Albert to try to move forward with where his foot is," Scioscia said. "He had some treatment on it after the game [Saturday] and with the off-day [Monday], he'll be further along on Tuesday."
Primarily a designated hitter for the first few weeks of the season, Pujols has seen more time at first base recently. The slugger has a .197 average in 16 games at first, compared to a .281 average in 14 games at DH.
Astros: Bedard transitions to bullpen
Erik Bedard saw his role change Sunday as the left-hander pitched 3 1/3 innings in relief. Before the game, Porter said Bedard was no longer in the rotation.
In five starts, Bedard is 0-2 with a 9.98 ERA. He tossed 3 1/3 innings of scoreless relief on Opening Day before moving into the rotation. On Sunday, Bedard allowed a solo home run and struck out three against two walks.
"I talked to Erik about it, and he took it well," Porter said. "His strikeouts are up and he's a guy you can bring in if you find a pocket with some lefties that it may be the back end of a game situation, or it may be a long situation where we have a lead going into the sixth inning, kind of like we did Opening Day, and can set up the closer."
• Angels outfielder Josh Hamilton is 4-for-7 (.571) in his career against Lyles with one homer and two RBIs.
• Astros first baseman Carlos Pena broke up Justin Verlander's no-hit bid with a single to right with one out in the seventh inning Sunday.